Native human Beta Thrombin protein (ab81591)
Key features and details
- Expression system: Native
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
-
Product name
Native human Beta Thrombin protein -
Biological activity
Purity
> 95 % SDS-PAGE.Expression system
NativeProtein length
Full length proteinAnimal free
NoNature
Native-
Species
Human -
Amino acids
328 to 622
Associated products
Specifications
Our Abpromise guarantee covers the use of ab81591 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
Functional Studies
SDS-PAGE
-
Form
Liquid -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 6.50
Constituents: 0.164% Sodium phosphate, 1.74% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
-
Alternative names
- Activation peptide fragment 1
- Activation peptide fragment 2
- Coagulation factor II
see all -
Relevance
Thrombin is an active enzyme in the earliest steps of the blood clot formation, generated from its circulating inactive precursor prothrombin. Thrombin is a glycoprotein formed by two peptides chains of 36 and 259 amino acids linked by disulfure bonds. Three important sites have been identified on the surface of the enzyme: The catalytic site that confers to the molecule its serine protease activity, the exosite one responsible for the binding of the substrate (fibrinogen or thrombin receptor) and the exosite two responsible for the binding of antithrombin III and inactivation of thrombin. Beta Thrombin is a proteolyzed form of Alpha Thrombin. -
Cellular localization
Secreted, extracellular space.
Images
-
SDS-PAGE - Native human Beta Thrombin protein (ab81591)Novex 4-12% Bis-Tris
1 µg per lane
MOPS
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab81591 has not yet been referenced specifically in any publications.
Preparation and Storage
-
Alternative names
- Activation peptide fragment 1
- Activation peptide fragment 2
- Coagulation factor II
see all -
Relevance
Thrombin is an active enzyme in the earliest steps of the blood clot formation, generated from its circulating inactive precursor prothrombin. Thrombin is a glycoprotein formed by two peptides chains of 36 and 259 amino acids linked by disulfure bonds. Three important sites have been identified on the surface of the enzyme: The catalytic site that confers to the molecule its serine protease activity, the exosite one responsible for the binding of the substrate (fibrinogen or thrombin receptor) and the exosite two responsible for the binding of antithrombin III and inactivation of thrombin. Beta Thrombin is a proteolyzed form of Alpha Thrombin. -
Cellular localization
Secreted, extracellular space.
Images
-
SDS-PAGE - Native human Beta Thrombin protein (ab81591)Novex 4-12% Bis-Tris
1 µg per lane
MOPS
