N6-Cyclopentyladenosine (CPA), A1 agonist (ab120398)
Key features and details
- Potent, selective A1 agonist
- CAS Number: 41552-82-3
- Purity: > 99%
- Soluble in 1 eq. HCl to 100 mM, in DMSO to 100 mM and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
N6-Cyclopentyladenosine (CPA), A1 agonist -
Description
Potent, selective A1 agonist -
Alternative names
- CPA
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Biological description
Potent and selective adenosine A1 receptor agonist (Ki values are 2.3, 790 and 43 nM for human A1, A2A and A3 receptors, respectively). Centrally active following systemic administration in vivo. Anticonvulsant, with cardiovacular actions, and effects on sleep regulation.
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Purity
> 99% -
CAS Number
41552-82-3 -
Chemical structure
Properties
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Chemical name
N-Cyclopentyladenosine -
Molecular weight
335.36 -
Molecular formula
C15H21N5O4 -
PubChem identifier
657378 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 1 eq. HCl to 100 mM, in DMSO to 100 mM and in ethanol to 25 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CCC(C1)NC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O -
Source
Synthetic
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Research areas
