N-Desmethyl clozapine (Normethylclozapine), Clozapine metabolite. M1 agonist. D2/D3 agonist. (ab120026)
Key features and details
- Clozapine metabolite. M1 agonist. D2/D3 agonist.
- CAS Number: 6104-71-8
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
N-Desmethyl clozapine (Normethylclozapine), Clozapine metabolite. M1 agonist. D2/D3 agonist. -
Description
Clozapine metabolite. M1 agonist. D2/D3 agonist. -
Alternative names
- Normethylclozapine
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Biological description
Brain penetrant metabolite of the atypical antipsychotic clozapine. Broad range of actions. Potent allosteric M1 partial agonist (IC50 = 55 nM for inhibition of [3H]-NMS binding). D2/D3 partial agonist. Also displays affinity at 5-HT1 and 5-HT2.
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Purity
> 99% -
CAS Number
6104-71-8 -
Chemical structure
