MS-1020, JAK3 inhibitor (ab141465)
Key features and details
- Selective, cell-permeable JAK3 inhibitor
- CAS Number: 1255516-86-9
- Purity: > 95%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
MS-1020, JAK3 inhibitor -
Description
Selective, cell-permeable JAK3 inhibitor -
Biological description
Selective JAK3 inhibitor. Potently inhibits persistently-active STAT3 in a cell type-specific manner. Downregulates anti-apoptotic gene expression. -
Purity
> 95% -
CAS Number
1255516-86-9 -
Chemical structure
Properties
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Chemical name
1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide -
Molecular weight
346.38 -
Molecular formula
C21H18N2O3 -
PubChem identifier
3725527 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC(=O)C1CN(C1)S(=O)(=O)C2=C(C=CC(=C2)OC)OC -
Source
Synthetic
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Research areas
