Call: +7 771 977 66 65, +7 705 421 2277
Sign in or Register
My basket

Astana Biomed Group, an authorized Abcam distributor in Central Asia

Abiomed homepage

  • Categories
    Signal Transduction
    Cancer
    Epigenetics and Nuclear Signaling
    Immunology
    Cell Biology
    Cardiovascular
    Neuroscience
    Tags & Cell Markers
    Kits/ Lysates/ Other
    Developmental Biology
    Microbiology
    Biochemicals
    Secondary antibodies
    Isotype/Loading Controls
    Antibody Arrays
  • About us
  • Partners
  • Contact
    Address

    Saryarka 32, 18, 010000, Astana city, Kazakhstan

    Telephone +7 771 977 66 65, +7 705 421 2277

    Email

    laboratory@ctlab.kz, orders@abiomed.kz

Back to category
Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Mouse SAPK3 Antibody Pair - BSA and Azide free (ab241712)

Mouse SAPK3 Antibody Pair - BSA and Azide free (ab241712)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Unconjugated capture and detector antibodies
  • Adaptable to any antibody pair-based assay format
  • Antibody concentration ~ 1 mg/ml
  • BSA and azide free buffer - ready for conjugation
  • Reacts with: Mouse

You may also be interested in

Product image
Anti-PINK1 antibody [EPR20730] - BSA and Azide free (ab232374)
Product image
Anti-Factor IX/PTC antibody - BSA and Azide free (ab281131)
Product image
Anti-OLFM4 antibody (ab105861)
Product image
Anti-Clathrin light chain antibody (ab103553)

Overview

  • Product name

    Mouse SAPK3 Antibody Pair - BSA and Azide free
    See all p38 gamma/MAPK12 kits
  • Assay type

    ELISA set
  • Range

    62.5 pg/ml - 4000 pg/ml
  • Species reactivity

    Reacts with: Mouse
  • Product overview

    The Antibody Pair can be used to quantify Mouse SAPK3. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.


    For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab208347), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.


    Download SDS here.

  • Tested applications

    Suitable for: Sandwich ELISAmore details
  • Platform

    Reagents

Properties

  • Storage instructions

    Store at +4°C. Please refer to protocols.
  • Carrier free

    Yes
  • Components 10 x 96 tests
    Mouse SAPK3 Capture Antibody (unconjugated) 1 x 100µg
    Mouse SAPK3 Detector Antibody (unconjugated) 1 x 100µg
  • Research areas

    • Cell Biology
    • Cell Cycle
    • Cell Cycle Inhibitors
    • Other
    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • MAPK Pathway
    • Cell Biology
    • Cell Cycle
    • Cell differentiation
  • Function

    Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.
  • Tissue specificity

    Highly expressed in skeletal muscle and heart.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • Domain

    The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • Post-translational
    modifications

    Dually phosphorylated on Thr-183 and Tyr-185, which activates the enzyme.
  • Cellular localization

    Cytoplasm. Mitochondrion. Mitochondrial when associated with SH3BP5.
  • Target information above from: UniProt accession P53778 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Alternative names

    • ERK 6
    • ERK-6
    • ERK6
    • Extracellular signal-regulated kinase 6
    • MAP kinase 12
    • MAP kinase p38 gamma
    • MAPK 12
    • Mapk12
    • Mitogen Activated Protein Kinase 12
    • Mitogen activated protein kinase p38 gamma
    • Mitogen-activated protein kinase 12
    • Mitogen-activated protein kinase p38 gamma
    • MK12_HUMAN
    • P38 GAMMA
    • P38GAMMA
    • PRKM12
    • SAPK 3
    • SAPK-3
    • SAPK3
    • Stress Activated Protein Kinase 3
    • Stress-activated protein kinase 3
    see all
  • Database links

    • Entrez Gene: 29857 Mouse
    • SwissProt: O08911 Mouse
    • Unigene: 38343 Mouse

    Images

    • Sandwich ELISA - Mouse SAPK3 Antibody Pair - BSA and Azide free (ab241712)
      Sandwich ELISA - Mouse SAPK3 Antibody Pair - BSA and Azide free (ab241712)
      To learn more about the advantages of recombinant antibodies see here.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Alternative products to Mouse SAPK3 Antibody Pair - BSA and Azide free (ab241712)

    •  
    • Product image

      Mouse MAPK 12 Matched Antibody Pair Kit (ab218177)

      Applications:

    Clear all

    Recently viewed products

    •  
    • Product image

      Anti-BST2/Tetherin antibody [EPR20202-169] (ab243229)

    •  
    • Product image

      Anti-eIF3A antibody [EPR5819(2)] - BSA and Azide free (ab248250)

    •  
    • Product image

      Anti-ZF21 antibody - N-terminal (ab189935)

    •  
    • Product image

      Anti-Integrin linked ILK antibody (ab227185)

    •  
    • Product image

      Anti-MMP1 antibody [EP1249Y] - BSA and Azide free (ab240086)

    •  
    • Product image

      Anti-FHIT antibody [EPR10931] - BSA and Azide free (ab249567)

    Get resources and offers direct to your inbox Sign up
    © 2021 Astana Biomed Group LLP. All rights reserved.