Montelukast sodium, leukotriene D4 antagonist (ab142323)
Key features and details
- Potent, selective leukotriene D4 antagonist
- CAS Number: 151767-02-1
- Purity: > 98%
- Soluble in water to 50 mM, in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Montelukast sodium, leukotriene D4 antagonist -
Description
Potent, selective leukotriene D4 antagonist -
Biological description
Potent, selective leukotriene D4 antagonist (Ki = 0.18 nM). Specific CysLT1 receptor antagonist. Shows anti-inflammatory and anti-Asthmatic effects. Orally active. Active in vitro and in vivo. -
Purity
> 98% -
CAS Number
151767-02-1 -
Chemical structure
Properties
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Chemical name
2-[1-[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate sodium salt -
Molecular weight
609.17 -
Molecular formula
C35H35ClNNaO3S -
PubChem identifier
23663996 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 50 mM, in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)[O-])O.[Na+] -
Source
Synthetic
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Research areas
