Monastrol, cell permeable mitosis inhibitor (ab141087)
Key features and details
- Potent and cell permeable mitosis inhibitor. Kinesin Eg5 inhibitor.
- CAS Number: 329689-23-8
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Monastrol, cell permeable mitosis inhibitor -
Description
Potent and cell permeable mitosis inhibitor. Kinesin Eg5 inhibitor. -
Biological description
Potent and cell permeable mitosis inhibitor. Arrests cellular mitosis through kinesin Eg5 inhibition (IC50 = 14 μM). Also slows ADP release, changes Eg5 conformation and alters Eg5 interactions with microtubules.
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Purity
> 99% -
CAS Number
329689-23-8 -
Chemical structure
