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Cancer Invasion/microenvironment Apoptosis Caspases

MMPSI, Caspase-3/7 Inhibitor I, caspase 3 and 7 inhibitor (ab145046)

Price and availability

338 390 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • Selective caspase 3 and 7 inhibitor
  • CAS Number: 220509-74-0
  • Purity: > 98%
  • Soluble in ethanol to 10 mM and in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    MMPSI, Caspase-3/7 Inhibitor I, caspase 3 and 7 inhibitor
  • Description

    Selective caspase 3 and 7 inhibitor
  • Biological description

    Selective caspase 3 and 7 inhibitor (IC50 = 1.7 μM, caspase-3). Reduces ischemic-induced apoptosis (IC50 = 0.5 μM). Shows cardioprotective effects.

  • Purity

    > 98%
  • CAS Number

    220509-74-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-[[(2S)-2-(Methoxymethyl)-1-pyrrolidinyl]sulfonyl]-1H-indole-2,3-dione
  • Molecular weight

    324.35
  • Molecular formula

    C14H16N2O5S
  • PubChem identifier

    9840223
  • Storage instructions

    Store at -20°C (desiccating conditions).
  • Solubility overview

    Soluble in ethanol to 10 mM and in DMSO to 100 mM
  • Handling

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    O=S(=O)(c1cc2C(=O)C(=O)Nc2cc1)N3CCC[C@H]3COC
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Intracellular
    • Caspases etc
    • Caspases
    • Cancer
    • Invasion/microenvironment
    • Apoptosis
    • Caspases
    • Cancer
    • Invasion/microenvironment
    • Apoptosis
    • Cytochrome C
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteolytic enzymes
    • Other proteases
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Caspase
    • Biochemicals
    • Pharmacology
    • Signaling
    • Apoptosis & cell cycle
    • Caspase
    • Metabolism
    • Pathways and Processes
    • Metabolism processes
    • Apoptosis
    • Cancer
    • Cell Death
    • Apoptosis
    • Apoptosis Markers
    • Caspases
    • Cancer
    • Cell Death
    • Apoptosis
    • Apoptosis Markers
    • Cytochrome C
    • Cancer
    • Cell Death
    • Apoptosis
    • Metabolism

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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