ML-SA1, TRPML agonist (ab144622)
Key features and details
- Selective TRPML agonist
- CAS Number: 332382-54-4
- Purity: > 98%
- Soluble in ethanol to 10 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ML-SA1, TRPML agonist -
Description
Selective TRPML agonist -
Biological description
Selective TRPML agonist. Induces TRPML1, 2 and 3-mediated Ca2+ release from lysosomes in vitro. Does not activate TRPM2, TRPV2, TRPA1, TRPV3, TRPC6 channels. Cell-permeable.
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Purity
> 98% -
CAS Number
332382-54-4 -
Chemical structure
Properties
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Chemical name
2-[2-(3,4-Dihydro-2,2,4-trimethyl-1(2H)-quinolinyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione -
Molecular weight
362.42 -
Molecular formula
C22H22N2O3 -
PubChem identifier
2880983 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C4c1ccccc1C(=O)N4CC(=O)N3c2ccccc2C(C)CC3(C)C -
Source
Synthetic
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Research areas