ML-324, JMJD2 inhibitor (ab146175)
Key features and details
- Potent, cell-permeable JMJD2 inhibitor
- CAS Number: 1222800-79-4
- Soluble in ethanol to 10 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ML-324, JMJD2 inhibitor -
Description
Potent, cell-permeable JMJD2 inhibitor -
Biological description
Potent, cell-permeable JMJD2 inhibitor (IC50 = 920 nM). Shows antiviral effects (IC50 = 10 μM), HSV-1 immediate early gene expression). Reversibly blocks human cytomegalovirus infection in vivo. -
CAS Number
1222800-79-4 -
Chemical structure
Properties
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Chemical name
N-[3-(Dimethylamino)propyl]-4-(8-hydroxyquinolin-6-yl)benzamide -
Molecular weight
349.43 -
Molecular formula
C21H23N3O2 -
PubChem identifier
44143209 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)CCCNC(=O)C1=CC=C(C=C1)C2=CC(=C3C(=C2)C=CC=N3)O -
Source
Synthetic
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Research areas
