MK 571 sodium salt (L 660711 sodium salt), CysLT1 receptor antagonist (ab144303)
Key features and details
- Potent, selective and competitive CysLT1 receptor antagonist
- CAS Number: 115104-28-4
- Purity: > 97%
- Soluble in water to 25 mM, in ethanol to 10 mM and in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
MK 571 sodium salt (L 660711 sodium salt), CysLT1 receptor antagonist -
Description
Potent, selective and competitive CysLT1 receptor antagonist -
Biological description
Potent, selective and competitive CysLT1 receptor antagonist (IC50 = 1.5 nM, LTD4). Potent MRP1 inhibitor. Shows anti-ischemic, anti-inflammatory and antinociceptive effects in vivo. Orally active. -
Purity
> 97% -
CAS Number
115104-28-4 -
Chemical structure
Properties
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Chemical name
3-[[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-[3-(dimethylamino)-3-oxopropyl]sulfanylmethyl]sulfanylpropanoate sodium salt -
Molecular weight
537.07 -
Molecular formula
C26H26ClN2NaO3S2 -
PubChem identifier
16760569 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in water to 25 mM, in ethanol to 10 mM and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)C(=O)CCSC(C1=CC=CC(=C1)C=CC2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)[O-].[Na+] -
Source
Synthetic
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Research areas
