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Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes Acetylation

MI-192 hydrochloride, HDAC2/3 inhibitor (ab146817)

Price and availability

381 945 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Key features and details

  • Selective HDAC2/3 inhibitor
  • CAS Number: 1415340-63-4
  • Purity: > 98%
  • Soluble in DMSO to 100 mM

  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    MI-192 hydrochloride, HDAC2/3 inhibitor
  • Description

    Selective HDAC2/3 inhibitor
  • Biological description

    Selective HDAC2/3 inhibitor. Regulates cytokine production from rheumatoid arthritis peripheral blood mononuclear cells (PBMCs). Shows anticancer effects in vitro.

  • Purity

    > 98%
  • General notes

    Sold under license from CRT.

  • CAS Number

    1415340-63-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-(2-Aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]benzamide hydrochloride

  • Molecular weight

    419.91
  • Molecular formula

    C24H21N3O2.HCl
  • PubChem identifier

    56965342
  • Storage instructions

    Store at -20°C (desiccating conditions).
  • Solubility overview

    Soluble in DMSO to 100 mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.Nc4ccccc4NC(=O)c1ccc(cc1)CN2CC(=C)c3ccccc3C2=O
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • Chromatin Modifying Enzymes
    • Acetylation
    • Stem Cells
    • Signaling Pathways
    • Wnt
    • HDACs
    • Epigenetics and Nuclear Signaling
    • Chromatin Modifying Enzymes
    • Acetylation
    • HDACs
    • Class I
    • Cancer
    • Oncoproteins/suppressors
    • Tumor suppressors
    • Other
    • Cardiovascular
    • Heart
    • Hypertrophy
    • Other
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Metabolism of lipids and lipoproteins
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipid metabolism

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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