MG-115 (DMSO solution), proteasome inhibitor (ab146625)
Key features and details
- Potent, reversible proteasome inhibitor
- CAS Number: 133407-86-0
- Purity: > 95%
- Supplied in DMSO (10 mM)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
MG-115 (DMSO solution), proteasome inhibitor -
Description
Potent, reversible proteasome inhibitor -
Biological description
Potent, reversible 20S and 26S proteasome inhibitor (Ki values are 21 and 35 nM, respectively). Inhibits chymotrypsin-like activity. Induces p53-dependent apoptosis in vitro.
Also available as a solid (ab142118). -
Purity
> 95% -
CAS Number
133407-86-0 -
Chemical structure
Properties
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Molecular weight
461.59 -
Molecular formula
C25H39N3O5 -
Sequence
LLX (Modifications: N-terminal benzyloxycarbonyl; C-terminal aldehyde; X-3 = Nva) -
PubChem identifier
9868928 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Supplied in DMSO (10 mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCC[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1 -
Source
Synthetic
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Research areas
