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Neuroscience Neurotransmission Receptors / Channels Ligand-Gated Ion Channels nAch Receptors

Methyllycaconitine citrate (MLA), alpha7 Nicotinic receptor antagonist (ab120072)

Price and availability

207 724 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Key features and details

  • α7 Nicotinic receptor antagonist
  • CAS Number: 112825-05-5
  • Purity: > 98%
  • Soluble in water to 100 mM

  • Form / State: Solid
  • Source: Delphinium

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Overview

  • Product name

    Methyllycaconitine citrate (MLA), alpha7 Nicotinic receptor antagonist
  • Description

    α7 Nicotinic receptor antagonist
  • Alternative names

    • MLA
  • Biological description

    Potent, selective antagonist at α7-containing nicotinic receptors.

    Also available in simple stock solutions (ab146684) - add 1 ml of water to get an exact, ready-to-use concentration.

  • Purity

    > 98%
  • CAS Number

    112825-05-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16-tetramethoxy-4-[[[2-(3-methyl-2,5-dioxo-1-pyrrolidinyl)benzoyl]oxy]methyl]aconitane-7,8-diol citrate

  • Molecular weight

    874.92
  • Molecular formula

    C37H50N2O10.C6H8O7
  • PubChem identifier

    90479749
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCN1C[C@@]2(CC[C@@H]([C@@]34[C@@H]1[C@@]([C@H](C23)OC)([C@]5(C[C@@H]([C@H]6C[C@@H]4[C@@H]5[C@H]6OC)OC)O)O)OC)COC(=O)C7=CC=CC=C7N8C(=O)C[C@@H](C8=O)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
  • Source

    Delphinium

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Ligand-Gated Ion Channels
    • nAch Receptors
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Nicotinic
    • α7
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Nicotinic
    • α7
    • Antagonists
    • Biochemicals
    • Research Area
    • Addiction
    • Nicotinic
    • α7
    • Biochemicals
    • Research Area
    • Addiction
    • Nicotinic
    • α7
    • Antagonists
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Nicotinic
    • α7
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Nicotinic
    • α7
    • Antagonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Nicotinic
    • α7
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Nicotinic
    • α7
    • Antagonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Nicotinic
    • α7
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Nicotinic
    • α7
    • Antagonists

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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