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Cancer Drug resistance Topoisomerases

Melphalan, Phenylamine derivative of mechorethamine (ab142635)

Key features and details

  • Alkylating agent. Phenylamine derivative of mechorethamine
  • CAS Number: 148-82-3
  • Purity: > 94%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Melphalan, Phenylamine derivative of mechorethamine
  • Description

    Alkylating agent. Phenylamine derivative of mechorethamine
  • Biological description

    Alkylating agent. Phenylamine derivative of mechorethamine. Attaches an alkyl group to the guanine base of DNA at the number 7 nitrogen atom of the imidazole ring. Active in vivo.
  • Purity

    > 94%
  • CAS Number

    148-82-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-2-Amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
  • Molecular weight

    305.20
  • Molecular formula

    C13H18Cl2N2O2
  • PubChem identifier

    460612
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Synthesis
    • Topoisomerases
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • DNA, RNA & protein synthesis
    • DNA & RNA synthesis

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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