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Marimastat, Matrix metalloprotease (MMP) inhibitor (ab141276)

Key features and details

  • Potent matrix metalloproteinase inhibitor
  • CAS Number: 154039-60-8
  • Purity: > 98%
  • Soluble in DMSO to 100 mM and in ethanol to 50 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Marimastat, Matrix metalloprotease (MMP) inhibitor
  • Description

    Potent matrix metalloproteinase inhibitor
  • Biological description

    Potent matrix metalloproteinase inhibitor. Broad-spectrum inhibitor of all major MMPs. Prevents or reduces spread and growth of tumors.

  • Purity

    > 98%
  • CAS Number

    154039-60-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide
  • Molecular weight

    331.41
  • Molecular formula

    C15H29N3O5
  • PubChem identifier

    119031
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    O[C@@H]([C@@H](CC(C)C)C(=O)N[C@H](C(=O)NC)C(C)(C)C)C(=O)NO
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Receptors
    • Receptor Processing
    • Cardiovascular
    • Angiogenesis
    • Adhesion / ECM
    • Matrix Metalloproteinases
    • MMP
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Alzheimer's disease
    • Other
    • Immunology
    • Innate Immunity
    • Cytokines
    • TNF Superfamily
    • Signal Transduction
    • Cytoskeleton / ECM
    • Extracellular Matrix
    • ECM Enzymes
    • MMP
    • Signal Transduction
    • Adapters
    • Transmembrane
    • Signal Transduction
    • Growth Factors/Hormones
    • TNF
    • Stem Cells
    • Signaling Pathways
    • Notch
    • Secreted
    • Signal Transduction
    • Cytoskeleton / ECM
    • Extracellular Matrix
    • ECM Enzymes
    • ADAM Protein Family
    • Cancer
    • Growth factors
    • TNF
    • Cancer
    • Invasion/microenvironment
    • Angiogenesis
    • ECM enzymes
    • MMPs
    • Cancer
    • Invasion/microenvironment
    • ECM
    • Extracellular matrix
    • ADAM protein family
    • Cancer
    • Invasion/microenvironment
    • ECM
    • Extracellular matrix
    • MMPs
    • Cancer
    • Signal transduction
    • Other
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteolytic enzymes
    • Metalloprotease
    • MMPs
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteolytic enzymes
    • Metalloprotease
    • ADAMs
    • Cancer
    • Tumor biomarkers
    • Enzymes
    • MMPs
    • Cardiovascular
    • Atherosclerosis
    • Thrombosis
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    • Atherosclerosis
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    • Metabolism
    • Types of disease
    • Metabolic disorders
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Protease
    • Matrix metalloprotease
    • Inhibitors
    • Biochemicals
    • Research Area
    • Cancer
    • Extracellular matrix & cell adhesion
    • Cell adhesion
    • Biochemicals
    • Research Area
    • Cancer
    • Extracellular matrix & cell adhesion
    • Focal adhesion kinase
    • Biochemicals
    • Research Area
    • Cancer
    • Extracellular matrix & cell adhesion
    • Matrix metalloprotease
    • Cancer
    • Cell Death
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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