Manoalide, phospholipase C (PLC) inhibitor (ab141554)
Key features and details
- Irreversible phospholipase C (PLC) inhibitor
- CAS Number: 75088-80-1
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Manoalide, phospholipase C (PLC) inhibitor -
Description
Irreversible phospholipase C (PLC) inhibitor -
Biological description
Irreversible phospholipase C (PLC) and phospholipase A2 (PLA2) inhibitor (IC50 values are 1.5 and 4.7 µM respectively) . Also shown to inhibit calcium channels. Anti-inflammatory and analgesic effects in vivo. -
Purity
> 98% -
CAS Number
75088-80-1 -
Chemical structure
Properties
-
Chemical name
2-Hydroxy-3-[6-hydroxy-5-[(E)-4-methyl-6-(2,6,6-trimethylcyclohexen-1-yl)hex-3-enyl]-3,6-dihydro-2H-pyran-2-yl]-2H-furan-5-one -
Molecular weight
416.60 -
Molecular formula
C25H36O5 -
PubChem identifier
5942250 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1=C(C(CCC1)(C)C)CCC(=CCCC2=CCC(OC2O)C3=CC(=O)OC3O)C -
Source
Synthetic
-
Research areas