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Immunology Innate Immunity Macrophage / Inflamm.

LY255283, BLT2 receptor antagonist (ab144472)

Key features and details

  • Selective, competitive BLT2 receptor antagonist
  • CAS Number: 117690-79-6
  • Purity: > 98%
  • Soluble in ethanol to 25 mM and in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    LY255283, BLT2 receptor antagonist
  • Description

    Selective, competitive BLT2 receptor antagonist
  • Biological description

    Selective, competitive BLT2 receptor antagonist (IC50 values are 1 and 10 μM for BLT2 and BLT1 respectively). Shows antiasthmatic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    117690-79-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone
  • Molecular weight

    360.50
  • Molecular formula

    C19H28N4O3
  • PubChem identifier

    122023
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 25 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCC1=C(C=C(C(=C1)C(=O)C)O)OCCCCCC(C)(C)C2=NNN=N2
  • Source

    Synthetic

  • Research areas

    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Cardiovascular
    • Blood
    • Other
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Other
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Immunology
    • Innate Immunity
    • Cytokines
    • Other
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    • Atherosclerosis
    • Lipoprotein metabolism
    • Biochemicals
    • Product Range
    • New
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    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Leukotriene & Related
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipoprotein metabolism
    • Metabolism
    • Types of disease
    • Heart disease

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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