Liraglutide, glucagon-like peptide-1(GLP-1) receptor agonist (ab231359)
Key features and details
- Long-acting glucagon-like peptide-1(GLP-1) receptor agonist.
- CAS Number: 204656-20-2
- Purity: > 99%
Soluble in water to 26.65 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Liraglutide, glucagon-like peptide-1(GLP-1) receptor agonist -
Description
Long-acting glucagon-like peptide-1(GLP-1) receptor agonist. -
Alternative names
- Liraglutida
- liraglutidum
- NN-2211
see all -
Biological description
Liraglutide is a long-acting analog of human glucagon-like peptide (GLP-1). It acts as a GLP-1 receptor agonist. Liraglutide attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecule expression in human vascular endothelial cells in vitro and may protect against endothelial cell dysfunction. Inhibits TNFα-induced ICAM-1 and VCAM-1 mRNA and protein expression by vascular enodothelial cell lines.
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Purity
> 99% -
CAS Number
204656-20-2 -
Chemical structure
Properties
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Chemical name
Glycine, L-?histidyl-?L-?alanyl-?L-?α-?glutamylglycyl-?L-?threonyl-?L-?phenylalanyl-?L-?threonyl-?L-?seryl-?L-?α-?aspartyl-?L-?valyl-?L-?seryl-?L-?seryl-?L-?tyrosyl-?L-?leucyl-?L-?α-?glutamylglycyl-?L-?glutaminyl-?L-?alanyl-?L-?alanyl-?N6-?[N-?(1-?oxohexadecyl)?-?L-?γ-?glutamyl]?-?L-?lysyl-?L-?α-?glutamyl-?L-?phenylalanyl-?L-?isoleucyl-?L-?alanyl-
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Molecular weight
3751.26 -
Sequence
HAEGTFTSDVSSYLEGQAAKEEFIIAWLVKGRG -
PubChem identifier
16134956 -
Storage instructions
Shipped at 4°C. Store at -20°C long term. -
Solubility overview
Soluble in water to 26.65 mM
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Source
Synthetic
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Research areas
