Leukotriene D4, CysLT1 and CysLT2 receptor agonist (ab141689)
Key features and details
- Potent, selective CysLT1 and CysLT2 receptor agonist
- CAS Number: 73836-78-9
- Purity: > 98%
- Supplied in methanol/ammonium acetate buffer, 70/30, pH 5.6 (50 µg/ml)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
Leukotriene D4, CysLT1 and CysLT2 receptor agonist -
Description
Potent, selective CysLT1 and CysLT2 receptor agonist -
Biological description
Potent, selective CysLT1 and CysLT2 receptor agonist (EC50 values are 1.12 and 0.99 nM, respectively. Induces bronchoconstriction and vasoconstriction. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
73836-78-9 -
Chemical structure
Properties
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Chemical name
(5S,6R,7E,9E,11Z,14Z)-6-[2-Amino-3-(carboxymethylamino)-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid -
Molecular weight
496.66 -
Molecular formula
C25H40N2O6S -
PubChem identifier
6435286 -
Storage instructions
Store at -80°C. -
Solubility overview
Supplied in methanol/ammonium acetate buffer, 70/30, pH 5.6 (50 µg/ml) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)N -
Source
Synthetic
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Research areas
