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Signal Transduction Cytoskeleton / ECM Cell Adhesion Integrins Alpha

Leukadherin-1, Integrin CD11b/CD19 agonist (ab142214)

Key features and details

  • Integrin CD11b/CD19 agonist
  • CAS Number: 344897-95-6
  • Purity: > 97%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Leukadherin-1, Integrin CD11b/CD19 agonist
  • Description

    Integrin CD11b/CD19 agonist
  • Biological description

    Integrin CD11b/CD19 agonist. Increases CD11b/CD18-dependent cell adhesion in vitro resulting in decreased chemotaxis and transendothelial migration. Decreases leukocyte recruitment and reduces arterial narrowing after injury. Preserves kidney function in vivo.
  • Purity

    > 97%
  • CAS Number

    344897-95-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[5-[(3-Benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]benzoic acid
  • Molecular weight

    421.49
  • Molecular formula

    C22H15NO4S2
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C(C=C1)CN2C(=O)C(=CC3=CC=C(O3)C4=CC=C(C=C4)C(=O)O)SC2=S
  • Source

    Synthetic

  • Research areas

    • Signal Transduction
    • Cytoskeleton / ECM
    • Cell Adhesion
    • Integrins
    • Alpha
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Enzyme-Linked Receptors
    • Integrin
    • Biochemicals
    • Pharmacology
    • Signaling
    • Extracellular matrix & cell adhesion
    • Cell adhesion
    • Biochemicals
    • Pharmacology
    • Signaling
    • Immunomodulators
    • Other

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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