LDN 193189 dihydrochloride (ab278073)
Key features and details
- Potent and selective inhibitor of ALK2 and ALK3
- CAS Number: 1435934-00-1
- Purity: > 99%
Soluble in water to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
LDN 193189 dihydrochloride -
Description
Potent and selective inhibitor of ALK2 and ALK3 -
Biological description
Potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.
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Purity
> 99% -
CAS Number
1435934-00-1 -
Chemical structure
Properties
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Chemical name
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline, hydrochloride
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Molecular weight
479.40 -
Molecular formula
C25H22N6.2HCl -
PubChem identifier
91900717 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. -
Solubility overview
Soluble in water to 10 mM
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl.Cl -
Source
Synthetic