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L-Mimosine, non-protein amino acid (ab145861)

Key features and details

  • Non-protein amino acid that acts as an iron chelator.
  • CAS Number: 500-44-7
  • Purity: > 98%
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    L-Mimosine, non-protein amino acid
  • Description

    Non-protein amino acid that acts as an iron chelator.
  • Alternative names

    • L-MIM
    • Leucenol
  • Biological description

    Toxic non-protein amino acid originally isolated from Mimosa pudica. Arrests the cell cycle at the G1 phase in PC-3 cells and at the S phase in LNCaP cells, thus attenuating cell proliferation. Blocks cell cycle progression by chelating iron in asynchronous MDA-MB-453 human breast cancer cells. Arrests DNA synthesis by inhibiting deoxyribonucleotide metabolism. Prolyl hydroxylase (PHD) inhibitor stimulating VEGF production, and increasing proangiogenic capacity in dental pulp-derived cells.

  • Purity

    > 98%
  • CAS Number

    500-44-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (S)-2-Amino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)propanoic acid

  • Molecular weight

    198.18
  • Molecular formula

    C8H10N2O4
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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