L 701324, glycine site NMDA receptor antagonist (ab146300)
Key features and details
- Potent, selective glycine site NMDA receptor antagonist
- CAS Number: 142326-59-8
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
L 701324, glycine site NMDA receptor antagonist -
Description
Potent, selective glycine site NMDA receptor antagonist -
Biological description
Potent, selective glycine site NMDA receptor antagonist. Shows a reduced propensity to activate mesolimbic dopaminergic systems compared to MK 801 (ab120027). Shows long-acting anticonvulsant effects in vivo. Orally active.
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Purity
> 99% -
CAS Number
142326-59-8 -
Chemical structure
Properties
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Chemical name
7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone -
Molecular weight
363.80 -
Molecular formula
C21H14ClNO3 -
PubChem identifier
54682505 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C=C1)OC2=CC=CC(=C2)C3=C(C4=C(C=C(C=C4)Cl)NC3=O)O -
Source
Synthetic
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Research areas
