kb-NB142-70, protein kinase D inhibitor (ab141773)
Key features and details
- Selective protein kinase D inhibitor
- CAS Number: 1233533-04-4
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
kb-NB142-70, protein kinase D inhibitor -
Description
Selective protein kinase D inhibitor -
Biological description
Selective protein kinase D inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). Inhibits prostrate cancer cell migration and invasion and reduces wound healing in vitro. Cytotoxic and anti-proliferative.
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Purity
> 99% -
CAS Number
1233533-04-4 -
Chemical structure
Properties
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Chemical name
3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one -
Molecular weight
251.32 -
Molecular formula
C11H9NO2S2 -
PubChem identifier
45258277 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CSC2=C(C(=O)N1)SC3=C2C=C(C=C3)O -
Source
Synthetic
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Research areas
