K252C, protein kinase C inhibitor (ab142312)
Key features and details
- Potent, cell-permeable protein kinase C inhibitor
- CAS Number: 85753-43-1
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
K252C, protein kinase C inhibitor -
Description
Potent, cell-permeable protein kinase C inhibitor -
Biological description
Potent, cell-permeable protein kinase C (PKC) inhibitor (IC50 are 2.45 and 25.7 μM for PKC and PKA respectively). Cytotoxic and antitumor agent. Active in vitro and in vivo. -
Purity
> 98% -
CAS Number
85753-43-1 -
Chemical structure
Properties
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Chemical name
6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one -
Molecular weight
311.34 -
Molecular formula
C20H13N3O -
PubChem identifier
3815 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C2=C3C4=CC=CC=C4NC3=C5C(=C2C(=O)N1)C6=CC=CC=C6N5 -
Source
Synthetic
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Research areas
