IWP-4 (ab278076)
Key features and details
- Potent inhibitor of Wnt
- CAS Number: 686772-17-8
- Purity: > 98%
Soluble in DMSO to 1 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IWP-4 -
Description
Potent inhibitor of Wnt -
Biological description
Potent inhibitor of Wnt pathway regulatory protein porupine (Porcn). Blocks Wnt protein secretion and prevents the canonical and non-canonical signaling pathways. Blocks palmitylation, and subsquent secretion and activity of Wnt. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.
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Purity
> 98% -
General notes
For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.
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CAS Number
686772-17-8 -
Chemical structure
Properties
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Chemical name
N-(6-Methyl-2-benzothiazolyl)-2-[[3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4- oxothieno[3,2-d]pyrimidin-2-yl]thio]acetamide
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Molecular weight
496.62 -
Molecular formula
C23H20N4O3S3 -
PubChem identifier
2155264 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 1 mM
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5OC)SCC4 -
Source
Synthetic
