ISRIB (trans-isomer) (ab273604)
Key features and details
- Potent and selective PERK inhibitor
- CAS Number: 1597403-47-8
- Purity: > 96%
Soluble in DMSO to 10 mM with gentle warming
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ISRIB (trans-isomer) -
Description
Potent and selective PERK inhibitor -
Biological description
Potent and selective PERK inhibitor with IC50 of 5 nM. Integrated stress response (ISR) inhibitor.
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Purity
> 96% -
CAS Number
1597403-47-8 -
Chemical structure
Properties
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Chemical name
N,N'-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]
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Molecular weight
451.34 -
Molecular formula
C22H24Cl2N2O4 -
PubChem identifier
1011240 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 10 mM with gentle warming
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Handling
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl -
Source
Synthetic
Images
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Chemical Structure - ISRIB (trans-isomer) (ab273604)
Chemical structure of ISRIB (trans-isomer), 1597403-47-8