Isotetrandrine, Cell-permeable PLA2 inhibitor (ab141626)
Key features and details
- Cell-permeable PLA2 inhibitor
- CAS Number: 477-57-6
- Purity: > 98%
- Soluble in DMSO to 25 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Isotetrandrine, Cell-permeable PLA2 inhibitor -
Description
Cell-permeable PLA2 inhibitor -
Biological description
Cytoplasmic phospholipase A2 (PLA2) inhibitor. Also shown to inhibit α1 adrenoceptor (Ki = 1.6 μM). Cell-permeable. Active in vivo. -
Purity
> 98% -
CAS Number
477-57-6 -
Chemical structure
Properties
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Chemical name
6',7,12-Tetramethoxy-2,2'-dimethylberbaman -
Molecular weight
622.80 -
Molecular formula
C38H42N2O6 -
PubChem identifier
5422 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC -
Source
Synthetic
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Research areas
- Biochemicals
- Research Area
- Heart disease
- Signaling
- Lipid signaling
- Phospholipase & Lipase
- Inhibitors
- Biochemicals
- Research Area
- Pain & inflammation
- Signaling
- Lipid signaling
- Phospholipase & Lipase
- Inhibitors
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Lipid signaling
- Phospholipase & Lipase
- Inhibitors