Isobarbituric acid, Uracil derative (ab145012)
Key features and details
- 5-hydroxy derivative of the nucleobase Uracil (ab143729) and an isomer of Barbituric Acid. Oxidative DNA damage biomarker.
- CAS Number: 496-76-4
- DMSO (Sparingly)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Isobarbituric acid, Uracil derative -
Description
5-hydroxy derivative of the nucleobase Uracil (ab143729) and an isomer of Barbituric Acid. Oxidative DNA damage biomarker. -
Alternative names
- 2,4,5-Trihydroxypyrimidine
- 5-Hydroxyuracil
- Dihydro-2,4,5(3H)-pyrimidinetrione
- NSC 95958
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Biological description
5-hydroxy derivative of the nucleobase Uracil (ab143729) and an isomer of Barbituric Acid. Studies show that it can form stable base pairs with all four bases in a DNA duplex. Used as an oxidative DNA damage biomarker.
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CAS Number
496-76-4 -
Chemical structure
Properties
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Chemical name
2,4,5-Trihydroxypyrimidine -
Molecular weight
128.09 -
Molecular formula
C4H4N2O3 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
DMSO (Sparingly) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
