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Neuroscience Neurotransmitter Biogenic Amines Dopamine

Isatin, MAOB inhibitor (ab142895)

Key features and details

  • Selective MAOB inhibitor. Potent ANP receptor antagonist
  • CAS Number: 91-56-5
  • Purity: > 97%
  • Soluble in water to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Isatin, MAOB inhibitor
  • Description

    Selective MAOB inhibitor. Potent ANP receptor antagonist
  • Biological description

    Selective endogenous MAOB inhibitor and potent ANP receptor antagonist (IC50 = 3-8 and 0.4 μM respectively). Inhibits alkaline phosphatase and (NO-stimulated soluble guanylate cyclase. Anxiolytic, sedative, anticonvulsant and antidiuretic effects in vivo. Blood-brain barrier permeable.
  • Purity

    > 97%
  • CAS Number

    91-56-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1H-Indole-2,3-dione
  • Molecular weight

    147.13
  • Molecular formula

    C8H5NO2
  • PubChem identifier

    7054
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C2C(=C1)C(=O)C(=O)N2
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Biogenic Amines
    • Dopamine
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Parkinson's disease
    • Other
    • Signal Transduction
    • Metabolism
    • Amino Acids
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Oxidases
    • MAO
    • Inhibitors
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Amino acid metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Drug metabolism
    • Metabolism
    • Types of disease
    • Neurodegenerative disease

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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