IPAG (1-(4-iodophenyl)-3-(2-adamantyl)guanidine), sigma1 antagonist (ab146440)
Key features and details
- Selective σ1 antagonist
- CAS Number: 193527-91-2
- Purity: > 99%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IPAG (1-(4-iodophenyl)-3-(2-adamantyl)guanidine), sigma1 antagonist -
Description
Selective σ1 antagonist -
Alternative names
- 1-(4-iodophenyl)-3-(2-adamantyl)guanidine
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Biological description
Selective σ1 antagonist (Ki = 8 μM). Shows GTP- and suramin-sensitive affinity binding. Induces cell death and inhibits tumor growth. Active in vitro and in vivo.
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Purity
> 99% -
CAS Number
193527-91-2 -
Chemical structure
Properties
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Chemical name
N-(4-Iodophenyl)-N'-tricyclo[3.3.1.13,7]dec-2-ylguanidine -
Molecular weight
395.29 -
Molecular formula
C17H22IN3 -
PubChem identifier
4239764 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C2CC3CC1CC(C2)C3N=C(N)NC4=CC=C(C=C4)I -
Source
Synthetic
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Research areas
