(-)-Indolactam V, PKC activator (ab144278)
Key features and details
- Potent PKC activator
- CAS Number: 90365-57-4
- Purity: > 97%
- Soluble in ethanol and in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(-)-Indolactam V, PKC activator -
Description
Potent PKC activator -
Biological description
Potent PKC activator (Ki values are 11, 6, 19, 8, 22, and 16 nM for α, β, γ, δ, ε, and η isozymes respectively). Induces pancreatic progenitor differentiation in embryonic stem cells. Shows tumorgenic effects in vivo. -
Purity
> 97% -
CAS Number
90365-57-4 -
Chemical structure
Properties
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Chemical name
(2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)- 3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one -
Molecular weight
301.38 -
Molecular formula
C17H23N3O2 -
PubChem identifier
105000 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. -
Solubility overview
Soluble in ethanol and in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)[C@H]1C(=O)N[C@@H](CC2=CNC3=C2C(=CC=C3)N1C)CO -
Source
Synthetic
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Research areas
