IKK-epsilon Kinase Inhibitor II, Inhibitor of IkappaB kinases (IKK) (ab142109)
Key features and details
- Inhibitor of IκB kinases (IKK)
- CAS Number: 862812-98-4
- Purity: > 97%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IKK-epsilon Kinase Inhibitor II, Inhibitor of IkappaB kinases (IKK) -
Description
Inhibitor of IκB kinases (IKK) -
Biological description
Key regulator of NF-κB signaling. Inhibitor of IκB kinases (IKK). One of three IKK isoforms-α, β, and ε-which have been linked to oncogenesis. -
Purity
> 97% -
CAS Number
862812-98-4 -
Chemical structure
Properties
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Chemical name
5-(5,6-Dimethoxybenzimidazol-1-yl)-3-[(2-methylsulfonylphenyl)methoxy]thiophene-2-carbonitrile -
Molecular weight
469.53 -
Molecular formula
C22H19N3O5S2 -
PubChem identifier
11626927 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C#N)OCC4=CC=CC=C4S(=O)(=O)C)OC -
Source
Synthetic
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Research areas
