IDE 2, endoderm formation inducer (ab145223)
Key features and details
- Cell-permeable definitive endoderm formation inducer
- CAS Number: 1136466-93-7
- Purity: > 98%
- Soluble in water to 20 mM, in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IDE 2, endoderm formation inducer -
Description
Cell-permeable definitive endoderm formation inducer -
Biological description
Cell-permeable definitive endoderm formation inducer (EC50 = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 (ab145222). Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo. -
Purity
> 98% -
CAS Number
1136466-93-7 -
Chemical structure
Properties
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Chemical name
7-(2-Cyclopentylidenehydrazinyl)-7-oxoheptanoic acid -
Molecular weight
240.30 -
Molecular formula
C12H20N2O3 -
PubChem identifier
23836158 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 20 mM, in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CCC(=NNC(=O)CCCCCC(=O)O)C1 -
Source
Synthetic
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Research areas