IBMX, Non-specific cAMP and cGMP inhibitor (ab120840)
Key features and details
- Non-specific cAMP and cGMP inhibitor
- CAS Number: 28822-58-4
- Purity: > 98%
- Soluble in DMSO to 75 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
IBMX, Non-specific cAMP and cGMP inhibitor -
Description
Non-specific cAMP and cGMP inhibitor -
Biological description
Non-specific cAMP and cGMP inhibitor -
Purity
> 98% -
CAS Number
28822-58-4 -
Chemical structure
Properties
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Chemical name
1-Methyl-3-(2-methylpropyl)-7H-purine-2,6-dione -
Molecular weight
222.24 -
Molecular formula
C10H14N4O2 -
PubChem identifier
3758 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2 -
Source
Synthetic
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Research areas
Images
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1e7 3T3-L1 cells were treated for 15 minutes with 1 µM dexamethasone (ab120743) and 1 µg x mL-1 insulin (ab123768) with the addition of 50 µM forskolin (ab120058), 0.5 mM IBMX (ab120840) or 0.1 mM 8-CPT-cAMP (ab120424), extracted according to the protocol. Lysates were diluted 50-fold, and tested in duplicates (+/-SD).