(-)-Huperzine A, AChE inhibitor (ab142238)
Key features and details
- AChE inhibitor and NMDA receptor antagonist
- CAS Number: 102518-79-6
- Purity: > 97%
- Soluble in DMSO and in ethanol
- Form / State: Solid
- Source: Huperzia serrata
Overview
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Product name
(-)-Huperzine A, AChE inhibitor -
Description
AChE inhibitor and NMDA receptor antagonist -
Alternative names
- Hup A
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Biological description
AChE inhibitor and non-competitive NMDA receptor antagonist (Ki = 6 μM, ion channel site). Shows anticonvulsant and antinociceptive effects in vivo. Blood-brain barrier permeable. -
Purity
> 97% -
CAS Number
102518-79-6 -
Chemical structure
Properties
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Chemical name
(1R,9S,13E)-1-Amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one -
Molecular weight
242.32 -
Molecular formula
C15H18N2O -
PubChem identifier
907504 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC=C1C2CC3=C(C1(CC(=C2)C)N)C=CC(=O)N3 -
Source
Huperzia serrata
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Research areas