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Cardiovascular Blood Fibrinolysis / Thrombolysis

Human uPAR Antibody Pair - BSA and Azide free (ab256694)

Human uPAR Antibody Pair - BSA and Azide free (ab256694)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Unconjugated capture and detector antibodies
  • Adaptable to any antibody pair-based assay format
  • Antibody concentration ~ 1 mg/ml
  • BSA and azide free buffer - ready for conjugation
  • Reacts with: Human

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Overview

  • Product name

    Human uPAR Antibody Pair - BSA and Azide free
    See all uPA Receptor/U-PAR kits
  • Assay type

    ELISA set
  • Range

    62.5 pg/ml - 4000 pg/ml
  • Species reactivity

    Reacts with: Human
  • Product overview

    The Antibody Pair can be used to quantify Human uPAR. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.


    For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab246549), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.


    Download SDS here.

  • Tested applications

    Suitable for: Sandwich ELISAmore details
  • Platform

    Reagents

Properties

  • Storage instructions

    Store at +4°C. Please refer to protocols.
  • Carrier free

    Yes
  • Components 10 x 96 tests
    Human uPAR Capture Antibody (unconjugated) 1 x 100µg
    Human uPAR Detector Antibody (unconjugated) 1 x 100µg
  • Research areas

    • Cardiovascular
    • Blood
    • Fibrinolysis / Thrombolysis
    • Immunology
    • Cell Type Markers
    • CD
    • Myeloid Cells
    • Cancer
    • Invasion/microenvironment
    • ECM
    • Extracellular matrix
    • Other
    • Cancer
    • Tumor biomarkers
    • Receptors
  • Function

    Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
  • Tissue specificity

    Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
  • Sequence similarities

    Contains 3 UPAR/Ly6 domains.
  • Cellular localization

    Secreted and Cell membrane.
  • Target information above from: UniProt accession Q03405 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Alternative names

    • CD 87
    • CD87
    • CD87 antigen
    • MO 3
    • MO3
    • Monocyte activation antigen Mo3
    • Plasminogen activator receptor urokinase
    • Plasminogen activator urokinase receptor
    • PLAUR
    • U PAR
    • u plasminogen activator receptor
    • U-PAR
    • u-plasminogen activator receptor form 2
    • UPA receptor
    • uPAR
    • UPAR_HUMAN
    • Urinary plasminogen activator receptor
    • URKR
    • Urokinase plasminogen activator receptor
    • Urokinase plasminogen activator surface receptor
    • urokinase-type plasminogen activator (uPA) receptor
    see all
  • Database links

    • Entrez Gene: 5329 Human
    • Omim: 173391 Human
    • SwissProt: Q03405 Human
    • Unigene: 466871 Human

    Images

    • Sandwich ELISA - Human uPAR Antibody Pair - BSA and Azide free (ab256694)
      Sandwich ELISA - Human uPAR Antibody Pair - BSA and Azide free (ab256694)
      To learn more about the advantages of recombinant antibodies see here.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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      Human uPAR ELISA Kit (ab246549)

      Applications:

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