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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Human TIA1 Antibody Pair - BSA and Azide free (ab244072)

Price and availability

670 ₸

Availability

Order now and get it on Friday March 05, 2021

Human TIA1 Antibody Pair - BSA and Azide free (ab244072)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Unconjugated capture and detector antibodies
  • Adaptable to any antibody pair-based assay format
  • Antibody concentration ~ 1 mg/ml
  • BSA and azide free buffer - ready for conjugation
  • Reacts with: Human

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Overview

  • Product name

    Human TIA1 Antibody Pair - BSA and Azide free
    See all TIA1 kits
  • Assay type

    ELISA set
  • Range

    188 pg/ml - 12000 pg/ml
  • Species reactivity

    Reacts with: Human
  • Product overview

    The Antibody Pair can be used to quantify Human TIA1. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.


    For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab231921), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.


    Download SDS here.

  • Tested applications

    Suitable for: Sandwich ELISAmore details
  • Platform

    Reagents

Properties

  • Storage instructions

    Store at +4°C. Please refer to protocols.
  • Carrier free

    Yes
  • Components 10 x 96 tests
    Human TIA1 Capture Antibody (unconjugated) 1 x 100µg
    Human TIA1 Detector Antibody (unconjugated) 1 x 100µg
  • Research areas

    • Cell Biology
    • Apoptosis
    • Nucleus
    • Other
    • Immunology
    • Adaptive Immunity
    • T Cells
    • Non-CD
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • RNA Processing
    • Other
    • Cancer
    • Cell Death
    • Apoptosis
    • Nucleus
    • Other
  • Function

    Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
  • Sequence similarities

    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localization

    Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.
  • Target information above from: UniProt accession P31483 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Alternative names

    • Cytotoxic granule associated RNA binding protein
    • Cytotoxic granule associated RNA binding protein 1
    • mTIA-1
    • Nucleolysin TIA 1 isoform p40
    • Nucleolysin TIA-1 isoform p40
    • Nucleolysin TIA1 isoform p40
    • p40 TIA 1
    • p40-TIA-1
    • p40-TIA-1 (containing p15-TIA-1)
    • RNA binding protein TIA 1
    • RNA binding protein TIA1
    • RNA-binding protein TIA-1
    • T-cell-restricted intracellular antigen-1
    • Tia
    • TIA 1
    • TIA 1 cytotoxic granule associated RNA binding protein
    • TIA-1
    • TIA1
    • TIA1 cytotoxic granule associated RNA binding protein
    • TIA1 cytotoxic granule associated RNA binding protein like 1
    • TIA1 protein
    • TIA1_HUMAN
    • TIAL1
    • TIAR
    • WDM
    see all
  • Database links

    • Entrez Gene: 7072 Human
    • Omim: 603518 Human
    • SwissProt: P31483 Human
    • Unigene: 413123 Human

    Images

    • Sandwich ELISA - Human TIA1 Antibody Pair - BSA and Azide free (ab244072)
      Sandwich ELISA - Human TIA1 Antibody Pair - BSA and Azide free (ab244072)
      To learn more about the advantages of recombinant antibodies see here.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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