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Human S100A11 knockout HeLa cell pellet (ab279208)

Overview

  • Product name

    Human S100A11 knockout HeLa cell pellet
    See all S100A11 kits

  • Product overview

    Abcam’s knockout cell pellets give you access to native proteins, without the need to culture cells. Our knockout cell pellets are prepared from our single-gene knockout cell lines and provide an additional offering to our cell lysates.

    Cells are snap-frozen to provide high quality pellets that are suitable for extraction with alternative lysis buffers or for preparation of lysates from subcellular fractions. Our knockout cell pellets are suitable for a variety of applications, including PCR, gene expression profiling and DNA library preparation.

  • Parental Cell Line

    HeLa

  • Organism

    Human

  • Mutation description

    Knockout achieved by using CRISPR/Cas9, 1 bp insertion in exon2.

  • Passage number

  • Knockout validation

    Sanger Sequencing

  • Notes

    Pellet size: 5 million cells/vial.

    This product is subject to limited use licenses from The Broad Institute, ERS Genomics Limited and Sigma-Aldrich Co. LLC, and is developed with patented technology. For full details of the licenses and patents please refer to our limited use license and patent pages.

Properties

Target

  • Function

    Facilitates the differentiation and the cornification of keratinocytes.

  • Sequence similarities

    Belongs to the S-100 family.
    Contains 2 EF-hand domains.

  • Post-translational
    modifications

    Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation.

  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt

  • Alternative names

    • Calgizzarin
    • Epididymis secretory protein Li 43
    • HEL S 43
    • Metastatic lymph node gene 70 protein
    • MLN 70
    • MLN70
    • Protein S100 A11
    • Protein S100-A11
    • Protein S100-A11, N-terminally processed
    • Protein S100-C
    • Protein S100A11
    • Protein S100C
    • S100 A11
    • S100 calcium binding protein A11
    • S100 calcium-binding protein A11
    • S100 calcium-binding protein A11 (calgizzarin)
    • S100a11
    • S100C
    • S10AB_HUMAN
    see all

Properties

Images

  • Sanger Sequencing - Human S100A11 knockout HeLa cell pellet (ab279208)
    Sanger Sequencing - Human S100A11 knockout HeLa cell pellet (ab279208)
    Homozygous: 1 bp insertion in exon2

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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