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Human NUP153 knockout HeLa cell pellet (ab279206)

Overview

  • Product name

    Human NUP153 knockout HeLa cell pellet
    See all Nup153 kits

  • Product overview

    Abcam’s knockout cell pellets give you access to native proteins, without the need to culture cells. Our knockout cell pellets are prepared from our single-gene knockout cell lines and provide an additional offering to our cell lysates.

    Cells are snap-frozen to provide high quality pellets that are suitable for extraction with alternative lysis buffers or for preparation of lysates from subcellular fractions. Our knockout cell pellets are suitable for a variety of applications, including PCR, gene expression profiling and DNA library preparation.

  • Parental Cell Line

    HeLa

  • Organism

    Human

  • Mutation description

    Knockout achieved by using CRISPR/Cas9, 10 bp deletion in exon3 and 2 bp insertion in exon3.

  • Passage number

  • Knockout validation

    Sanger Sequencing

  • Notes

    Pellet size: 5 million cells/vial.

    This product is subject to limited use licenses from The Broad Institute, ERS Genomics Limited and Sigma-Aldrich Co. LLC, and is developed with patented technology. For full details of the licenses and patents please refer to our limited use license and patent pages.

Properties

Target

  • Function

    Possible DNA-binding subunit of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane.

  • Sequence similarities

    Contains 4 RanBP2-type zinc fingers.

  • Domain

    Contains F-X-F-G repeats.

  • Cellular localization

    Nucleus > nuclear pore complex. Located to the terminal ring structure of the nucleoplasmic cage.
  • Information by UniProt

  • Alternative names

    • 153 kDa nucleoporin
    • HNUP153
    • N153
    • NU153_HUMAN
    • Nuclear pore complex protein hnup153
    • Nuclear pore complex protein Nup153
    • Nucleoporin 153kDa
    • Nucleoporin Nup153
    • Nup 153
    • Nup153
    see all

Properties

Images

  • Sanger Sequencing - Human NUP153 knockout HeLa cell pellet (ab279206)
    Sanger Sequencing - Human NUP153 knockout HeLa cell pellet (ab279206)

    Allele-1: 10 bp deletion in exon3

     

  • Sanger Sequencing - Human NUP153 knockout HeLa cell pellet (ab279206)
    Sanger Sequencing - Human NUP153 knockout HeLa cell pellet (ab279206)

    Allele-2: 2 bp insertion in exon3

     

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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