Human ICA 512 / PTPRN Antibody Pair - BSA and Azide free (ab244039)
Key features and details
- Unconjugated capture and detector antibodies
- Adaptable to any antibody pair-based assay format
- Antibody concentration ~ 1 mg/ml
- BSA and azide free buffer - ready for conjugation
- Reacts with: Human
Overview
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Product name
Human ICA 512 / PTPRN Antibody Pair - BSA and Azide free
See all ICA 512/PTPRN kits -
Assay type
ELISA set -
Range
31.25 pg/ml - 2000 pg/ml -
Species reactivity
Reacts with: Human -
Product overview
The Antibody Pair can be used to quantify Human PTPRN. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.
For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab226903), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.
Download SDS here.
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Tested applications
Suitable for: Sandwich ELISAmore details -
Platform
Reagents
Properties
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Storage instructions
Store at +4°C. Please refer to protocols. -
Carrier free
Yes -
Components 10 x 96 tests Human ICA 512 / PTPRN Capture Antibody (unconjugated) 1 x 100µg Human ICA 512 / PTPRN Detector Antibody (unconjugated) 1 x 100µg -
Research areas
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Function
Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. -
Tissue specificity
Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary. -
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
Contains 1 tyrosine-protein phosphatase domain. -
Post-translational
modificationsAppears to undergo multiple proteolytic cleavage at consecutive basic residues. -
Cellular localization
Membrane. Neuroendocrine secretory granules. - Information by UniProt
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Alternative names
- CA 512
- FLJ16131
- IA 2
see all -
Database links
- Entrez Gene: 5798 Human
- Omim: 601773 Human
- SwissProt: Q16849 Human
- Unigene: 89655 Human
Images
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Sandwich ELISA - Human ICA 512 / PTPRN Antibody Pair - BSA and Azide free (ab244039)To learn more about the advantages of recombinant antibodies see here.
