Human Ficolin-2 ELISA Kit (ab213778)
Key features and details
- Sensitivity: 20 pg/ml
- Range: 0.78 ng/ml - 50 ng/ml
- Sample type: Cell culture supernatant, Hep Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components Identifier 1 x 96 tests ABC Diluent Buffer Blue Cap 1 x 12ml Adhesive Plate Seal 4 units Antibody Diluent Buffer Green Cap 1 x 12ml Anti-Human Ficolin-2 coated Microplate (12 x 8 wells) 1 unit Avidin-Biotin-Peroxidase Complex (ABC) 1 x 100µl Biotinylated anti-Human Ficolin-2 antibody 1 x 130µl Lyophilized recombinant Human Ficolin-2 standard 2 vials Sample Diluent Buffer Green Cap 1 x 30ml TMB Color Developing Agent Black Cap 1 x 10ml TMB Stop Solution Yellow Cap 1 x 10ml -
Research areas
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Function
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. -
Tissue specificity
Expressed by the liver and secreted in plasma. -
Sequence similarities
Belongs to the ficolin lectin family.
Contains 1 collagen-like domain.
Contains 1 fibrinogen C-terminal domain. -
Domain
The fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding. -
Cellular localization
Secreted. - Information by UniProt
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Alternative names
- 37 kDa elastin-binding protein
- Collagen/fibrinogen domain containing protein 2
- Collagen/fibrinogen domain-containing protein 2
see all -
Database links
- Entrez Gene: 2220 Human
- Entrez Gene: 2220 Human
- Omim: 601624 Human
- SwissProt: Q15485 Human
- SwissProt: Q15485 Human
- Unigene: 54517 Human
Images
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Human Ficolin-2 ELISA Kit (ab213778) Standard Curve.
Human Ficolin-2 ELISA Kit (ab213778) Standard Curve.