Human C5 / C5b peptide (ab46169)
Key features and details
- Suitable for: Blocking
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Product name
Human C5 / C5b peptide -
Animal free
No -
Nature
Synthetic -
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Species
Human
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Preparation and Storage
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Alternative names
- C5
- Complement C5
- Complement component 5
- CPAMD4
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Relevance
C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kDa glycoprotein consisting of a disulphide linked alpha-chain (115kDa) and beta-chain (75kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain). -
Cellular localization
Secreted