Astana Biomed Group, an authorized Abcam distributor in Central Asia

Human ARID2 knockout HeLa cell pellet (ab279138)

Overview

  • Product name

    Human ARID2 knockout HeLa cell pellet
    See all ARID2 kits

  • Product overview

    Abcam’s knockout cell pellets give you access to native proteins, without the need to culture cells. Our knockout cell pellets are prepared from our single-gene knockout cell lines and provide an additional offering to our cell lysates.

    Cells are snap-frozen to provide high quality pellets that are suitable for extraction with alternative lysis buffers or for preparation of lysates from subcellular fractions. Our knockout cell pellets are suitable for a variety of applications, including PCR, gene expression profiling and DNA library preparation.

  • Parental Cell Line

    HeLa

  • Organism

    Human

  • Mutation description

    Knockout achieved by using CRISPR/Cas9, 1 bp deletion in exon2.

  • Passage number

  • Knockout validation

    Sanger Sequencing

  • Notes

    Pellet size: 5 million cells/vial.

    This product is subject to limited use licenses from The Broad Institute and ERS Genomics Limited, and is developed with patented technology. For full details of the limited use licenses and relevant patents please refer to our limited use license and patent pages.

Properties

Target

  • Function

    Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.

  • Tissue specificity

    Highly expressed in heart and testis.

  • Sequence similarities

    Contains 1 ARID domain.
    Contains 1 C2H2-type zinc finger.
    Contains 1 RFX-type winged-helix DNA-binding domain.

  • Developmental stage

    Up-regulated in adult heart (at protein level).

  • Cellular localization

    Nucleus.
  • Information by UniProt

  • Alternative names

    • ARID domain containing protein 2
    • ARID domain-containing protein 2
    • ARID2
    • ARID2_HUMAN
    • AT rich interactive domain 2 (ARID, RFX like)
    • AT rich interactive domain containing protein 2
    • AT-rich interactive domain-containing protein 2
    • BAF
    • BAF200
    • BRG1 associated factor 200
    • BRG1-associated factor 200
    • DKFZp686G052
    • DKFZp779P0222
    • FLJ30619
    • KIAA1557
    • p200
    • Zinc finger protein with activation potential
    • zip zap
    • zipzap
    • Zipzap/p200
    see all

Properties

Images

  • Sanger Sequencing - Human ARID2 knockout HeLa cell pellet (ab279138)
    Sanger Sequencing - Human ARID2 knockout HeLa cell pellet (ab279138)
    Homozygous: 1 bp deletion in exon2

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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