HA14-1, Bcl-2 inhibitor. BH-3 mimetic. (ab141306)
Key features and details
- Cell permeable Bcl-2 inhibitor. BH-3 mimetic.
- CAS Number: 65673-63-4
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
HA14-1, Bcl-2 inhibitor. BH-3 mimetic. -
Description
Cell permeable Bcl-2 inhibitor. BH-3 mimetic. -
Biological description
Cell permeable Bcl-2 inhibitor. BH-3 mimetic. Disrupts Bax and Bcl-2 interactions. Apoptotic anticancer agent.
-
CAS Number
65673-63-4 -
Chemical structure
Properties
-
Chemical name
2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester -
Molecular weight
409.23 -
Molecular formula
C17H17BrN2O5 -
PubChem identifier
3549 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
O=C(OCC)C(C#N)C1c2cc(Br)ccc2OC(N)=C1C(=O)OCC -
Source
Synthetic
-
Research areas
