GSK2656157 (ab273622)
Key features and details
- Potent and selective PERK inhibitor
- CAS Number: 1337532-29-2
- Purity: >= 98%
Soluble in DMSO to 50 mM
- Source: Synthetic
Overview
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Product name
GSK2656157 -
Description
Potent and selective PERK inhibitor -
Biological description
Potent and selective PERK inhibitor (IC50 = 0.9 nM in cell-free assay). ATP-competitive. Exibits 500-fold selectivity for PERK versus a panel of 300 kinases.
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Purity
>= 98% -
CAS Number
1337532-29-2 -
Chemical structure
Properties
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Chemical name
1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)ethanone
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Molecular weight
416.45 -
Molecular formula
C23H21FN6O -
PubChem identifier
53469059 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 50 mM
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C -
Source
Synthetic
Images
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Chemical Structure - GSK2656157 (ab273622)
Chemical structure of GSK2656157, 1337532-29-2
