Astana Biomed Group, an authorized Abcam distributor in Central Asia

GSK2656157 (ab273622)

Key features and details

  • Potent and selective PERK inhibitor
  • CAS Number: 1337532-29-2
  • Purity: >= 98%

  • Soluble in DMSO to 50 mM

  • Source: Synthetic

Overview

  • Product name

    GSK2656157

  • Description

    Potent and selective PERK inhibitor

  • Biological description

    Potent and selective PERK inhibitor (IC50 = 0.9 nM in cell-free assay). ATP-competitive. Exibits 500-fold selectivity for PERK versus a panel of 300 kinases. 

  • Purity

    >= 98%

  • CAS Number

    1337532-29-2

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)ethanone

  • Molecular weight

    416.45

  • Molecular formula

    C23H21FN6O

  • PubChem identifier

    53469059

  • Storage instructions

    Shipped at room temperature. Store at -20°C.

  • Solubility overview

    Soluble in DMSO to 50 mM

  • Handling

    Refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C

  • Source

    Synthetic

Images

  • Chemical Structure - GSK2656157 (ab273622)
    Chemical Structure - GSK2656157 (ab273622)

    Chemical structure of GSK2656157, 1337532-29-2

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