GSK-J4, histone demethylase JMJD3/UTX inhibitor (ab144395)
Key features and details
- Cell permeable histone demethylase JMJD3/UTX inhibitor
- CAS Number: 1373423-53-0
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 100mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GSK-J4, histone demethylase JMJD3/UTX inhibitor -
Description
Cell permeable histone demethylase JMJD3/UTX inhibitor -
Alternative names
- Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoate
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Purity
> 98% -
CAS Number
1373423-53-0 -
Chemical structure
Properties
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Chemical name
N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester -
Molecular weight
417.51 -
Molecular formula
C24H27N5O2 -
PubChem identifier
71729974 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC(=O)CCNC1=NC(=NC(=C1)N2CCC3=CC=CC=C3CC2)C4=CC=CC=N4.Cl -
Source
Synthetic
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Research areas