GSK-J1, H3K27 histone demethylase inhibitor (ab144396)
Key features and details
- Potent and selective H3K27 histone demethylase inhibitor
- CAS Number: 1373422-53-7
- Purity: > 99%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GSK-J1, H3K27 histone demethylase inhibitor -
Description
Potent and selective H3K27 histone demethylase inhibitor -
Alternative names
- 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoic acid
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Purity
> 99% -
CAS Number
1373422-53-7 -
Chemical structure
Properties
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Chemical name
N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine -
Molecular weight
389.46 -
Molecular formula
C22H23N5O2 -
PubChem identifier
56963315 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
OC(=O)CCNC1=CC(=NC(=N1)C1=NC=CC=C1)N1CCC2=C(CC1)C=CC=C2 -
Source
Synthetic
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Research areas
