GS 39783, GABAB positive allosteric modulator (ab120320)
Key features and details
- Novel, GABAB positive allosteric modulator
- CAS Number: 39069-52-8
- Purity: > 99%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GS 39783, GABAB positive allosteric modulator -
Description
Novel, GABAB positive allosteric modulator -
Biological description
Novel, GABAB positive allosteric modulator (EC50 = 3 μM for [35S]GTPγS binding). Shows anxiolytic and antiaddictive effects in vivo. Blood-brain barrier permeable. Orally active.
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Purity
> 99% -
CAS Number
39069-52-8 -
Chemical structure
Properties
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Chemical name
N4,N6-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine -
Molecular weight
337.44 -
Molecular formula
C15H23N5O2S -
PubChem identifier
6604928 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CSC1=NC(=C(C(=N1)NC2CCCC2)[N+](=O)[O-])NC3CCCC3 -
Source
Synthetic
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Research areas
